Patented Liver Support | Evidence Based | Results Driven 

Patented Liver Support Evidence Based
Results Driven

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available Mon-Fri 9AM-4PM Arizona Time
Want to speak with one of our Product experts?
available Mon-Fri 9AM-4PM Arizona Time

SINCE 2019 LiverFlo Has Been Changing Lives for the Better. LiverFlo is Professionally Formulated. The Patented Formulation and Advanced Delivery System Provide 
Outstanding Performance and Better Results. 

Recommended by Physicians and Healthcare Practitioners 

Our goal in creating LiverFlo was to make Fatty Liver Obsolete (FLO). LiverFlo is an Advanced and Patented breakthrough in liver health. The four active ingredients in LiverFlo are generally accepted and administered worldwide. Evidenced Based and Professionally formulated, Liverflo’s clinically significant ingredients and pharmaceutical grade delivery system provide the nutritional and metabolic intervention you need for outstanding liver support. 

Should You Be Taking LiverFlo?

YES!  If you are serious about your liver and achieving good health! LiverFlo is a serious product intended for serious people concerned about healthy liver function. There is nothing comparable to LiverFlo available anywhere. Liverflo is simply the most advanced and effective liver health product in the world. And this includes pharmaceutical medications. There are currently no drugs available to address the complex metabolic needs of a sluggish and poorly functioning liver. The liver requires a more integrative and multi-faceted approach to be effective and successful. Healthy lifestyle changes that include more complex whole food nutrients and regular exercise are essential, but not always enough and often too difficult to follow and sustain for many people. LiverFlo is Clinically Significant Nutritional Intervention to support healthy liver metabolism and function.  

Effective | Convenient | Affordable | Essential 

How Much is Good Health 
Worth to You?

LiverFlo Does Not Cut Corners! Unlike other products that compromise on quality and quantity to keep the price down' LiverFlo uses expensive pharmaceutical grade extracts at therapeutic dose levels for all of the active ingredients.  

LiverFlo is Evidence Based! Unlike other products that throw 50 random ingredients at very low doses into a formulation because it looks good in the marketing, LiverFlo leverages 4 Clinically Significant Ingredients based on Valid Scientific Research and has dosed them to the evidence-based recommendations presented in human clinical trials. 

LiverFlo is Advanced Liver Science! Unlike other products that utilize poorly bioavailable ingredients at less than therapeutic doses, LiverFlo leverages our 40 years of phospholipid experience in a very thoughtful "DUAL PHASE" and Advanced Sub-Micron (NANO TECH) delivery system that is ingredient specific and designed to maximize both phases of absorption to significantly increase ingredient absorption and bioavailability!  

LiverFlo Stands Alone! Unlike other "Me Too" products that are cheaply formulated and unremarkable, we can tell you without hesitation that there is no other product anywhere in the world that compares to LiverFlo in quality, delivery technology          and results.  

LiverFlo Provides Incredible Value!  Unlike other products that are overpriced and ineffective, Liverflo delivers the goods at a remarkable price.  

Less Than a Cup of Starbucks Coffee!
How much is good health worth to you? For most of us good health is priceless and now for less than a cup of Starbucks Coffee you can give yourself a chance at better health. LiverFlo has proven itself to be a New Breakthrough in Liver Health and Function. Your liver is the Tree of Life that feeds nearly all other organs and when your liver is working properly, your whole body has a chance to work properly. LiverFlo not only supercharges your liver, but its health benefits extend to every cell and organelle in your body...all 50 Trillion of them +/-. The clinically significant and pharmaceutical grade ingredients, therapeutic dosing, and advanced delivery system that make LiverFlo so effective for the liver, also provide holistic benefits that help to protect your cells from damages caused by induced metabolic dysfunction, inflammation and oxidative stress.  And LiverFlo gives your cells what they need to restructure, repair, regenerate and proliferate.  Healthy cell metabolism and function is restored and when that happens...Look Out...Because better health is just around the corner! 

 "You can have all the riches and success in the world, but if you don't have your health, you have nothing." WC

SINCE 2019 LiverFlo Has Been Changing Lives for the Better. LiverFlo is Professionally Formulated. The Patented Formulation and Advanced Delivery System Provide 
Outstanding Performance and Better Results. 

Recommended by Physicians and Healthcare Practitioners 

Our goal in creating LiverFlo was to make Fatty Liver Obsolete (FLO). LiverFlo is an Advanced and Patented breakthrough in liver health. The four active ingredients in LiverFlo are generally accepted and administered worldwide. Evidenced Based and Professionally formulated, Liverflo’s clinically significant ingredients and pharmaceutical grade delivery system provide the nutritional and metabolic intervention you need for outstanding liver support. 

Should You Be Taking LiverFlo?

YES!  If you are serious about your liver and achieving good health! LiverFlo is a serious product intended for serious people concerned about healthy liver function. There is nothing comparable to LiverFlo available anywhere. Liverflo is simply the most advanced and effective liver health product in the world. And this includes pharmaceutical medications. There are currently no drugs available to address the complex metabolic needs of a sluggish and poorly functioning liver. The liver requires a more integrative and multi-faceted approach to be effective and successful. Healthy lifestyle changes that include more complex whole food nutrients and regular exercise are essential, but not always enough and often too difficult to follow and sustain for many people. LiverFlo is Clinically Significant Nutritional Intervention to support healthy liver metabolism and function.  

Effective | Convenient | Affordable | Essential 

How Much is Good Health 
Worth to You?

LiverFlo Does Not Cut Corners! Unlike other products that compromise on quality and quantity to keep the price down' LiverFlo uses expensive pharmaceutical grade extracts at therapeutic dose levels for all of the active ingredients.  

LiverFlo is Evidence Based! Unlike other products that throw 50 random ingredients at very low doses into a formulation because it looks good in the marketing, LiverFlo leverages 4 Clinically Significant Ingredients based on Valid Scientific Research and has dosed them to the evidence-based recommendations presented in human clinical trials. 

LiverFlo is Advanced Liver Science! Unlike other products that utilize poorly bioavailable ingredients at less than therapeutic doses, LiverFlo leverages our 40 years of phospholipid experience in a very thoughtful "DUAL PHASE" and Advanced Sub-Micron (NANO TECH) delivery system that is ingredient specific and designed to maximize both phases of absorption to significantly increase ingredient absorption and bioavailability!  

LiverFlo Stands Alone! Unlike other "Me Too" products that are cheaply formulated and unremarkable, we can tell you without hesitation that there is no other product anywhere in the world that compares to LiverFlo in quality, delivery technology          and results.  

LiverFlo Provides Incredible Value!  Unlike other products that are overpriced and ineffective, Liverflo delivers the goods at a remarkable price.  

Less Than a Cup of Starbucks Coffee!
How much is good health worth to you? For most of us good health is priceless and now for less than a cup of Starbucks Coffee you can give yourself a chance at better health. LiverFlo has proven itself to be a New Breakthrough in Liver Health and Function. Your liver is the Tree of Life that feeds nearly all other organs and when your liver is working properly, your whole body has a chance to work properly. LiverFlo not only supercharges your liver, but its health benefits extend to every cell and organelle in your body...all 50 Trillion of them +/-. The clinically significant and pharmaceutical grade ingredients, therapeutic dosing, and advanced delivery system that make LiverFlo so effective for the liver, also provide holistic benefits that help to protect your cells from damages caused by induced metabolic dysfunction, inflammation and oxidative stress.  And LiverFlo gives your cells what they need to restructure, repair, regenerate and proliferate.  Healthy cell metabolism and function is restored and when that happens...Look Out...Because better health is just around the corner! 

 "You can have all the riches and success in the world, but if you don't have your health, you have nothing." WC

If You Are Going to Make the Effort... Make It Count!

When you compare LiverFlo to the active ingredients when purchased separately it becomes clear. LiverFlo delivers exceptional quality, technology and results with Zero Risk and a 100 Percent Satisfaction Guarantee. 


Better Health is Just Around the Corner and It's Possible with LiverFlo

The Road to Good Health Runs Through the Liver!  Don't let your sluggish liver get in the way of living your best life now!

Holistic and Physiological 
With Liverflo you can quickly and conveniently counteract and repair the cellular membrane damages contributing to liver dysfunction.  The active ingredients in Liverflo are readily incorporated into the liver cell membranes and support the restructuring, repair, and regeneration of damaged cells that lead to poor cellular metabolism and poor liver function.

Convenient and Effective
Taking just 3 Liverflo capsules twice daily may be all you need to do to tip the scale in your liver's favor in order to supercharge your livers recovery and healthy function.  

Scientifically Valid
Over 500 scientifically valid studies have demonstrated the significant synergistic effects of SAMe and PPC, SAMe and silymarin, silymarin and glycyrrhizin, and silymarin and PPC and especially in alcoholic and non-alcoholic fatty liver, and hepatic intoxication resulting from nutritional imbalances, pharmaceutical drugs, pollutant substances, viruses and other toxic and other harmful environmental influences.  

Professional Validation
Since Receiving a Patent in January of 2019 LiverFlo is gaining noteworthy attention among healthcare practitioners and is quickly becoming the best-selling liver health supplement in the United States. 

Simply the Best
Liverflo is simply the most advanced and most effective Liver health product on the market – in any category – anywhere on the planet. 

Everything to gain and nothing to lose.
A healthy well-functioning liver is the key to good health and optimal wellness. With LiverFlo your journey to good health may get the kick start it needs to succeed.  Give yourself the chance.  Try LiverFlo today. You have everything to gain and nothing to lose. Absolutely ZERO RISK as We guarantee your satisfaction 100 Percent

Life Changing Liver Health Support 

LiverFlo is Pharmaceutical Grade Liver Support

Designed to support healthy liver function LiverFlo is also a holistic powerhouse. Your whole-body benefits from LiverFlo as it works throughout the body to restructure and repair cell membranes and to restore cell metabolism and function.  As cell membrane damages occur in many disorders, LiverFlo's therapeutic approach is both physiological and holistic.  

LiverFlo is particularly active and beneficial:

As a Liver Cell Membrane Therapy, the active compounds in LiverFlo work to Restructure Damaged Cell Membranes, Normalize Cell Membrane Permeability, Activate Membrane Bound Enzymes and Receptors, Restore Healthy Liver Cell Metabolism and Stimulate Liver Cell Regeneration and Detoxification* 
The Only Advanced Patented Liver System
4 in 1 Support
Liverflo® is a Proven Synergistic Combination of Four (4) Pharmaceutical Grade and Therapeutically Dosed Ingredients, delivered in a nano emulsion of Phosphatidylcholine and a Delayed Release, Dual Capsule (Capsule inside a Capsule) Technology. Our Delivery System is designed to ensure the highest absorption rates, increased bioavailability and the Best Results! 

If You Are Going to Make the Effort... Make It Count!

When you compare LiverFlo to the active ingredients when purchased separately it becomes clear. LiverFlo delivers exceptional quality, technology and results with Zero Risk and a 100 Percent Satisfaction Guarantee. 


Better Health is Just Around the Corner and It's Possible with LiverFlo

The Road to Good Health Runs Through the Liver!  Don't let your sluggish liver get in the way of living your best life now!

Holistic and Physiological 
With Liverflo you can quickly and conveniently counteract and repair the cellular membrane damages contributing to liver dysfunction.  The active ingredients in Liverflo are readily incorporated into the liver cell membranes and support the restructuring, repair, and regeneration of damaged cells that lead to poor cellular metabolism and poor liver function.

Convenient and Effective
Taking just 3 Liverflo capsules twice daily may be all you need to do to tip the scale in your liver's favor in order to supercharge your livers recovery and healthy function.  

Scientifically Valid
Over 500 scientifically valid studies have demonstrated the significant synergistic effects of SAMe and PPC, SAMe and silymarin, silymarin and glycyrrhizin, and silymarin and PPC and especially in alcoholic and non-alcoholic fatty liver, and hepatic intoxication resulting from nutritional imbalances, pharmaceutical drugs, pollutant substances, viruses and other toxic and other harmful environmental influences.  

Professional Validation
Since Receiving a Patent in January of 2019 LiverFlo is gaining noteworthy attention among healthcare practitioners and is quickly becoming the best-selling liver health supplement in the United States. 

Simply the Best
Liverflo is simply the most advanced and most effective Liver health product on the market – in any category – anywhere on the planet. 

Everything to gain and nothing to lose.
A healthy well-functioning liver is the key to good health and optimal wellness. With LiverFlo your journey to good health may get the kick start it needs to succeed.  Give yourself the chance.  Try LiverFlo today. You have everything to gain and nothing to lose. Absolutely ZERO RISK as We guarantee your satisfaction 100 Percent

Life Changing Liver Health Support 

LiverFlo is Pharmaceutical Grade Liver Support

Designed to support healthy liver function LiverFlo is also a holistic powerhouse. Your whole-body benefits from LiverFlo as it works throughout the body to restructure and repair cell membranes and to restore cell metabolism and function.  As cell membrane damages occur in many disorders, LiverFlo's therapeutic approach is both physiological and holistic.  

LiverFlo is particularly active and beneficial:

As a Liver Cell Membrane Therapy, the active compounds in LiverFlo work to Restructure Damaged Cell Membranes, Normalize Cell Membrane Permeability, Activate Membrane Bound Enzymes and Receptors, Restore Healthy Liver Cell Metabolism and Stimulate Liver Cell Regeneration and Detoxification* 
The Only Advanced Patented Liver System
4 in 1 Support
Liverflo® is a Proven Synergistic Combination of Four (4) Pharmaceutical Grade and Therapeutically Dosed Ingredients, delivered in a nano emulsion of Phosphatidylcholine and a Delayed Release, Dual Capsule (Capsule inside a Capsule) Technology. Our Delivery System is designed to ensure the highest absorption rates, increased bioavailability and the Best Results! 

The Story Behind LiverFlo 

LiverFlo (Fatty Liver Obsolete - FLO) is a One-Of-A-Kind Liver Support Supplement developed and patented by Nutrasal, Inc. and a Team of European Doctors with specialties in phospholipids, phytomedicine and hepatology.

Research and Development
Led by Dr. Karl J. Gundermann a leading hepatologist and world-renowned phospholipid guru; the team researched thousands of clinical studies from around the globe and over 50 different ingredient combinations were investigated. Much to the surprise of our Doctors, Only Four (4) of these natural compounds had been studied together. And there are over 500 clinical studies to demonstrate that when these active ingredients are administered together, the synergistic effect results in additional & clinically significant liver health benefits.  

Once we identified these 4 compounds as being the most synergistic and effective liver compounds when administered together, we committed to developing the most advanced and effective liver product on the planet.

The end result is a pharmaceutical grade liver supplement 
designed to deliver outstanding results. 

A Breakthrough in Liver Support and Function
The final result of our research and development is four 
(4) clinically significant compounds, professionally formulated and optimally dosed. And all based on clinical results and recommendations. 

What makes LiverFlo even more special is that these clinically significant ingredients are administered in our revolutionary, ingredient specific delivery system that is So Unique and So Effective it was awarded a US Patent.
(US Patent No: 10,172,801 Bl - Issued January 8, 2019)
Advanced Formulation and Capsule Technology
An advanced Dual Capsule (Capsule Inside a Capsule), and sub-micron (Nano Tech) actives guarantees the best possible absorption & bioavailability for each ingredient.* 

1st Phase: Outer Capsule is for Immediate Release of PPC, Silymarin and glycyrrhicinic acid. 

2nd Phase: Inner Capsule | Enteric Coated for delayed release of S-Adenosylmethionine (SAMe) and PPC. 
A Breakthrough in Liver Support and Function
The combination of four proven and clinically significant ingredients, a micronized PPC delivery system (nano tech)  and a delayed release dual capsule technology (DCT) to increase absorption and bioavailability is what separates Liverflo from all others and establishes Liverflo as a  New Breakthrough in All Natural Liver Support and Function*

Developed By Nutrasal 

A Top 5 Global Producer of Phosphatidylcholine

Nutrasal, Inc. was ranked by Industry Market Monitor as A Top 5 Global Producer of Phospholipids and Phosphatidylcholine. We are the manufacturer of PhosChol. Since 1982 PhosChol has remained the number one selling pharmaceutical grade PPC in the United States with Hundreds of Millions of Doses Sold to Doctors in the United States alone.  PhosChol is Purified PPC (Polyenyl-Phosphatidylcholine - Pharmaceutical Grade) and until LiverFlo came along, it stood alone at the only Dietary Supplement to Contain the same Oil Seed Medicinal found in two registered pharmaceutical drugs sold globally. 
(Source: National Resource Council - Ottawa, Canada)

LiverFlo contains 1800mg of PPC per dose. The registered therapeutic dose for PPC (PhosChol). 

The Story Behind LiverFlo 

LiverFlo (Fatty Liver Obsolete - FLO) is a One-Of-A-Kind Liver Support Supplement developed and patented by Nutrasal, Inc. and a Team of European Doctors with specialties in phospholipids, phytomedicine and hepatology.

Research and Development
Led by Dr. Karl J. Gundermann, the team researched thousands of clinical studies from around the globe and over 50 different ingredient combinations were investigated. Much to the surprise of our Doctors, Only Four (4) natural compounds out of Fifty (50) total had clinically significant data available (over 500 clinical studies) to demonstrate that if these active compounds were combined and administered together, they could provide additional and clinically significant liver health benefits.  

Once we identified these 4 compounds as being the most synergistic and effective liver compounds when administered together, we committed to developing the most advanced and effective liver product on the planet.

The end result is a pharmaceutical grade liver supplement 
designed to deliver outstanding results. 

A Breakthrough in Liver Support and Function
The final result of our research and development is four 
(4) clinically significant compounds, professionally formulated and optimally dosed. And all based on clinical results and recommendations. 

What makes LiverFlo even more special is that these clinically significant ingredients are administered in our revolutionary, ingredient specific delivery system that is So Unique and So Effective it was awarded a US Patent.
(US Patent No: 10,172,801 Bl - Issued January 8, 2019)
Advanced Formulation and Capsule Technology
An advanced Dual Capsule (Capsule Inside a Capsule), and sub-micron (Nano Tech) actives guarantees the best possible absorption & bioavailability for each ingredient.* 

1st Phase: Outer Capsule is for Immediate Release of PPC, Silymarin and glycyrrhicinic acid. 

2nd Phase: Inner Capsule | Enteric Coated for delayed release of S-Adenosylmethionine (SAMe) and PPC. 
A Breakthrough in Liver Support and Function
The combination of four proven and clinically significant ingredients, a micronized PPC delivery system (nano tech)  and a delayed release dual capsule technology (DCT) to increase absorption and bioavailability is what separates Liverflo from all others and establishes Liverflo as a  New Breakthrough in All Natural Liver Support and Function*

Developed By Nutrasal 

A Top 5 Global Producer of Phosphatidylcholine

Nutrasal, Inc. was ranked by Industry Market Monitor as A Top 5 Global Producer of Phospholipids and Phosphatidylcholine. We are the manufacturer of PhosChol. Since 1982 PhosChol has remained the number one selling pharmaceutical grade PPC in the United States with Hundreds of Millions of Doses Sold to Doctors in the United States alone.  PhosChol is Purified PPC (Polyenyl-Phosphatidylcholine - Pharmaceutical Grade) and until LiverFlo came along, it stood alone at the only Dietary Supplement to Contain the same Oil Seed Medicinal found in two registered pharmaceutical drugs sold globally. 
(Source: National Resource Council - Ottawa, Canada)

LiverFlo contains 1800mg of PPC per dose. The registered therapeutic dose for PPC (PhosChol). 

Clinically Significant
Nutritional Intervention In Support of Healthy Liver Function
CUSTOM JAVASCRIPT / HTML
*Click to view label and nutritional information.
LiverFlo 2 Pack: 4-in-1 Support
  • 2 LiverFlo Bottles 180 Capsules (Month Supply)
  • ​3 Capsules Twice Daily is Considered the Therapeutic Dose. 
  • ​​Two Bottles Per Month are Required for Recommended Use.
  • ​3 Capsules Once Daily is Considered an Aid to Good Health.
  • Multi Bottle Volume Discounts are Available. Check for Details.
  • Multi Product Fortified Bundles are Available at Reduced Pices.
LiverFlo Bundle 1: Liver Support Pack
  •  2 LiverFlo & 1 Liposome BComplex (Month Supply)
  • ​Added B Complex with MethyFolate, supports improved methylation and cell metabolism.
LiverFlo Bundle 2: LiverFlo Forte - The Liver Protocol
  •  2 LiverFlo, 1 Liposome B Complex & 1 60ct. PPC (Month Supply)
  • ​Added B Complex with MethyFolate, supports improved methylation and cell metabolism.
  • ​Added PPC (1200mg/day) brings daily intake up to 3000mg.    Human Clinical studies over 70 years have shown additional benefits at slightly higher doses of three (3) grams per day. (Liverflo Contains the registered therapeutic dose of PPC is 1800mg/day).

Repair and Restore 

More than 500 clinical studies confirm the synergistic effects and positive health benefits of the 4 active ingredients in Liverflo by:*

1:   Increasing Blood Flow Properties*
2:  Reducing Radicals and Peroxides*
3:  Increasing Aminopropylation, Transsulfuration                   and Transmethylation*  
4:  Inhibiting hepatic toxicity by outside influences such       as poor diet, alcohol, prescription drugs*
5:  Supporting liver cell repair, restructure and                         regeneration*
6:  Optimizing liver cell metabolic functions*
7:  Increasing Glutathione Production in the Liver                     Naturally by Restoring Depleted SAMe (S-Adenosyl-         Methionine) Levels*
8:  Improving antioxidative response and liver detox*
9:  Restructuring Damaged Cell Membranes,                             Normalizing Cell Permeability, Activating Membrane         Bound Enzymes and Receptors and by Improving             Cell Metabolism*
10: Stimulating Liver Cell Detoxification & Regeneration* 

.... And So much More!

Professionally Formulated and Dosed | Evidence Based 

Active Ingredients: polyenylphosphatidylcholine (Purified PPC), glycyrrhizin (Purified Licorice Root Extract), silymarin (Purified Milk Thistle Extract) and 
S-adenosyl-L-methionine (SAMe).

Effective | Convenient | Affordable | Essential 

Clinically Significant
Nutritional Intervention In Support of Healthy Liver Function
CUSTOM JAVASCRIPT / HTML
*Click to view label and nutritional information.
LiverFlo 2 Pack: 4-in-1 Support
  • 2 LiverFlo Bottles 180 Capsules (Month Supply)
  • ​3 Capsules Twice Daily is Considered the Therapeutic Dose. 
  • ​​Two Bottles Per Month are Required for Recommended Use.
  • ​3 Capsules Once Daily is Considered an Aid to Good Health.
  • Multi Bottle Volume Discounts are Available. Check for Details.
  • Multi Product Fortified Bundles are Available at Reduced Pices.
LiverFlo Bundle 1: Liver Support Pack
  •  2 LiverFlo & 1 Liposome BComplex (Month Supply)
  • ​Added B Complex with MethyFolate, supports improved methylation and cell metabolism.
LiverFlo Bundle 2: 
LiverFlo Forte | The Liver Protocol
  •  2 LiverFlo, 1 Liposome B Complex & 1 60ct. PPC (Month Supply)
  • ​Added B Complex with MethyFolate, supports improved methylation and cell metabolism.
  • ​Added PPC (1200mg/day) brings daily intake up to 3000mg.    Human Clinical studies over 70 years have shown additional benefits at slightly higher doses of three (3) grams per day. (Liverflo Contains the registered therapeutic dose of PPC is 1800mg/day).

Repair and Restore 

More than 500 clinical studies confirm the synergistic effects and positive health benefits of the 4 active ingredients in Liverflo by:*

1:   Increasing Blood Flow Properties*
2:  Reducing Radicals and Peroxides*
3:  Increasing Aminopropylation, Transsulfuration                   and Transmethylation*  
4:  Inhibiting hepatic toxicity by outside influences such       as poor diet, alcohol, prescription drugs*
5:  Supporting liver cell repair, restructure and                         regeneration*
6:  Optimizing liver cell metabolic functions*
7:  Increasing Glutathione Production in the Liver                     Naturally by Restoring Depleted SAMe (S-Adenosyl-         Methionine) Levels*
8:  Improving antioxidative response and liver detox*
9:  Restructuring Damaged Cell Membranes,                             Normalizing Cell Permeability, Activating Membrane         Bound Enzymes and Receptors and by Improving             Cell Metabolism*
10: Stimulating Liver Cell Detoxification & Regeneration* 

.... And So much More!

Professionally Formulated and Dosed | Evidence Based 

Active Ingredients: polyenylphosphatidylcholine (Purified PPC), glycyrrhizin (Purified Licorice Root Extract), silymarin (Purified Milk Thistle Extract) and 
S-adenosyl-L-methionine (SAMe).

Effective | Convenient | Affordable | Essential 

3 Amazing Liver Saving Options

LiverFlo Essential Protocol

LiverFlo Essentials 2 Pack 
Patented, Advanced 
4-in-1 Support

LiverFlo Essentials Fortified with Liposomal B Complex, Methyl Folate, Biotin & L-Carnitine

LiverFlo Essentials Fortified with Liposomal B Complex and PhosChol PPC

3 Amazing Liver Saving Options

LiverFlo Essential Protocol

LiverFlo Essentials 2 Pack 
Patented, Advanced 
4-in-1 Support

LiverFlo Essentials Fortified with Liposomal B Complex, Methyl Folate, Biotin & L-Carnitine

LiverFlo Essentials Fortified with Liposomal B Complex and PhosChol PPC

LiverFlo: Active Ingredients

Pharmaceutical Grade & Clinically Dosed 
The Power of Synergy and Delivery
The 4 Active Ingredients in LiverFlo were chosen specifically for their proven liver health benefits. And these ingredients are the ONLY LIVER HEALTH AGENTS with clinical evidence proving Better Results are Achieved when administered together at therapeutic dose Levels. Add in our Advanced Sub-Micron, Multi-Phase Delivery System and you get IMPROVED SYNERGY | PERFORMANCE | RESULTS! 
PPC: Polyenyl-Phosphatidylcholine
PPC is 100% purified and pharmaceutical grade phosphatidylcholine. PPC has the highest concentration of a very special and therapeutic molecule called 1,2-DLPC, which accounts for its superior results. PPC significantly improves membrane dependent cellular and organ functions. As a cell membrane therapeutic PPC restructures damaged cell membranes, normalizes cell permeability, improves cell metabolism, reactivates membrane bound enzymes & stimulates cell and liver cell regeneration 
When you take PPC (PhosChol)
  • You’ll flood your liver with Life Giving and Liver Saving molecules to improve liver cell metabolism and function.
  • You’ll get all of the therapeutic cell membrane benefits that are well established for over 70 years. Pharmaceutical Grade PPC has been an approved liver drug in 50 Plus Countries since 1953.   
  • You’ll get the most highly concentrated All-Natural and most effective Liver Health and Anti-Aging product used by the best Doctors in functional, complementary and alternative medicine. Over 200 million Doses have been Sold to Doctors in the United States alone.
  • Your Liver Cells will get what they need to Restructure, Repair, Reactivate and Regenerate. 
  • You’ll benefit from this Foundational Whole-Body Molecule that has been called “A Miracle Anti-Aging Molecule and The Closest Thing to the Fountain of Youth” by top doctors in functional and anti-aging medicine.  
DLPC corresponds to the body’s own homemade source of phosphatidylcholine 
with the primary and critical function of cell membrane construction

LiverFlo: Active Ingredients

Pharmaceutical Grade & Clinically Dosed 
The Power of Synergy and Delivery
The 4 Active Ingredients in LiverFlo were chosen specifically for their proven liver health benefits. And these ingredients are the ONLY LIVER HEALTH AGENTS with clinical evidence proving Better Results are Achieved when administered together at therapeutic dose Levels. Add in our Advanced Sub-Micron, Multi-Phase Delivery System and you get IMPROVED SYNERGY | PERFORMANCE | RESULTS! 
PPC: Polyenyl-Phosphatidylcholine
PPC is 100% purified and pharmaceutical grade phosphatidylcholine. PPC has the highest concentration of a very special and therapeutic molecule called 1,2-DLPC, which accounts for its superior results. PPC significantly improves membrane dependent cellular and organ functions. As a cell membrane therapeutic PPC restructures damaged cell membranes, normalizes cell permeability, improves cell metabolism, reactivates membrane bound enzymes & stimulates cell and liver cell regeneration 
When you take PPC (PhosChol)
  • You’ll flood your liver with Life Giving and Liver Saving molecules to improve liver cell metabolism and function.
  • You’ll get all of the therapeutic cell membrane benefits that are well established for over 70 years. Pharmaceutical Grade PPC has been an approved liver drug in 50 Plus Countries since 1953.   
  • You’ll get the most highly concentrated All-Natural and most effective Liver Health and Anti-Aging product used by the best Doctors in functional, complementary and alternative medicine. Over 200 million Doses have been Sold to Doctors in the United States alone.
  • Your Liver Cells will get what they need to Restructure, Repair, Reactivate and Regenerate. 
  • You’ll benefit from this Foundational Whole-Body Molecule that has been called “A Miracle Anti-Aging Molecule and The Closest Thing to the Fountain of Youth” by top doctors in functional and anti-aging medicine.  
DLPC corresponds to the body’s own homemade source of phosphatidylcholine 
with the primary and critical function of cell membrane construction
Silymarin: Purified Milk Thistle
Silymarin is extracted from the ripe fruits of milk thistle (Silybum marianum). It contains the combination of the isomeric flavonolignans silydianin, silychristin, isosilybinin and silybinin, with the latter being the most biologically active.

Among its many benefits Silymarin exerts membrane-stabilizing and antioxidant activity, reduces inlflammatory reactions and promotes liver cell regeneration.
When you take Siymarin
  • You’ll flood your Liver with the most concentrated and potent herbal extract used by alternative physicians and traditional Chinese medicine to promote healthy liver function.
  • You’ll have powerful and proven liver protection against cellular lipid and membrane damages from various forms of injurious influences.
  • You’ll have proven and powerful support that helps liver cells regenerate – especially in the case of pending loss of liver cells.
  • Your liver will be reinforced against environmental toxins and cellular toxicity. You’ll enjoy Liver and Whole-Body support and restoration of the Antioxidant Network. 
Silymarin: Purified Milk Thistle
Silymarin is extracted from the ripe fruits of milk thistle (Silybum marianum). It contains the combination of the isomeric flavonolignans silydianin, silychristin, isosilybinin and silybinin, with the latter being the most biologically active.

Among its many benefits Silymarin exerts membrane-stabilizing and antioxidant activity, reduces inlflammatory reactions and promotes liver cell regeneration.
When you take Siymarin
  • You’ll flood your Liver with the most concentrated and potent herbal extract used by alternative physicians and traditional Chinese medicine to promote healthy liver function.
  • You’ll have powerful and proven liver protection against cellular lipid and membrane damages from various forms of injurious influences.
  • You’ll have proven and powerful support that helps liver cells regenerate – especially in the case of pending loss of liver cells.
  • Your liver will be reinforced against environmental toxins and cellular toxicity. You’ll enjoy Liver and Whole-Body support and restoration of the Antioxidant Network. 
Glycyrrhizin from Glycyrrhiza Glabra
Licorice Root is one of the most ancient medicinal plants; it has long been used in traditional Chinese medicine for the treatment of various inflammatory disorders.

Glycyrrhizin (GL) is a major bioactive triterpene glycoside of licorice root extract and has a variety of beneficial and pharmacological properties. Among them is its ability to slow down rapid cellular degeneration brought about by circulating free radicals and oxidative stress.
When you take Glycyrrhizin
  • You’ll flood your liver with the highest concentrated and most therapeutic source of GL available. Glycyrrhizin, like Silymarin has long been used in Traditional Chinese Medicine and by alternative healthcare practitioners to promote healthy liver function.
  • You’ll get all the liver health benefits provided by a molecule used for 1000's of years for its anti-inflammatory, antioxidant and immune modulating/boosting properties. 
  • You’ll provide your liver the help it needs to stabilize cellular/lysosomal membranes, inhibit cathepsin B expression and enzyme activity, inhibit mitochondrial cytochrome c release, and reduce FFA-induced oxidative stress.
  • You will fortify your liver with a special ingredient that has proven its worth as a liver protective compound for inducing endogenous interferon formation and other beneficial health effects. 
Glycyrrhizin from Glycyrrhiza Glabra
Licorice Root is one of the most ancient medicinal plants; it has long been used in traditional Chinese medicine for the treatment of various inflammatory disorders.

Glycyrrhizin (GL) is a major bioactive triterpene glycoside of licorice root extract and has a variety of beneficial and pharmacological properties. Among them is its ability to slow down rapid cellular degeneration brought about by circulating free radicals and oxidative stress.
When you take Glycyrrhizin
  • You’ll flood your liver with the highest concentrated and most therapeutic source of GL available. Glycyrrhizin, like Silymarin has long been used in Traditional Chinese Medicine and by alternative healthcare practitioners to promote healthy liver function.
  • You’ll get all the liver health benefits provided by a molecule used for 1000's of years for its anti-inflammatory, antioxidant and immune modulating/boosting properties. 
  • You’ll provide your liver the help it needs to stabilize cellular/lysosomal membranes, inhibit cathepsin B expression and enzyme activity, inhibit mitochondrial cytochrome c release, and reduce FFA-induced oxidative stress.
  • You will fortify your liver with a special ingredient that has proven its worth as a liver protective compound for inducing endogenous interferon formation and other beneficial health effects. 
S-Adenosyl-L-Methionine (SAMe)
SAMe is a metabolically significant molecule that participates in multiple cellular reactions. It is the primary precursor for synthesis of glutathione, the major defense mechanism against oxidative stress. SAMe is particularly important in opposing the toxicity of free radical species generated by various pathogens which cause oxidative stress. SAMe improves metabolic pathways including Transmethylation, Transsulfuration, & Aminopropylation. Depleted SAMe is associated with poor liver health.  
When you take SAMe
  • You’ll flood your liver with this Metabolically Significant and “Essential Nutrient” responsible for multiple and critical cellular reactions.
  • You’ll get substantial metabolic support to increase Glutathione, the major physiologic defense mechanism against oxidative stress!
  • You’ll get additional Whole-Body support improving mitochondrial function and especially in the liver cells where SAMe synthesis is essential but depleted in sluggish livers.
  • You’ll get significant support for the liver to increase Transmethylation, Transulfruation, and Aminoprophylations, all critical synthesis pathways for the proper function and regenerative capabilities of the liver.
S-Adenosyl-L-Methionine (SAMe)
SAMe is a metabolically significant molecule that participates in multiple cellular reactions. It is the primary precursor for synthesis of glutathione, the major defense mechanism against oxidative stress. SAMe is particularly important in opposing the toxicity of free radical species generated by various pathogens which cause oxidative stress. SAMe improves metabolic pathways including Transmethylation, Transsulfuration, & Aminopropylation. Depleted SAMe is associated with poor liver health.  
When you take SAMe
  • You’ll flood your liver with this Metabolically Significant and “Essential Nutrient” responsible for multiple and critical cellular reactions.
  • You’ll get substantial metabolic support to increase Glutathione, the major physiologic defense mechanism against oxidative stress!
  • You’ll get additional Whole-Body support improving mitochondrial function and especially in the liver cells where SAMe synthesis is essential but depleted in sluggish livers.
  • You’ll get significant support for the liver to increase Transmethylation, Transulfruation, and Aminoprophylations, all critical synthesis pathways for the proper function and regenerative capabilities of the liver.
So Let’s Sum it All Up
More than 500 clinical publications confirm the pharmacological results of the 4 compounds polyenylphosphatidylcholine, glycyrrhicinic acid, silymarin and s-adenosyl-L-methionine in Liverflo by:
  • inhibiting hepatic toxicity by air pollution, industrial toxins, nutrients and malnutrition, drugs, and hormone
  • reducing the risk to develop an alcoholic or non-alcoholic fatty liver disease, hepatitis and hepatic fibrosis or cirrhosis 
  • optimizing hepatocellular metabolic functions 
Why is the combination of the 4 active ingredients in Liverflo so special? Why does Liverflo have a synergistic unique mode of action beyond those described for each ingredient, leading to a breakthrough in hepatic functioning and protection?

First, the administration of PPC alone has been an approved drug since 1953 and is being sold today in over 50 countries around the world by a leading pharmaceutical company. (not available in the US)

Second, silymarin and Glycyrrhiza glabra have limited bioavailability, but co-administered with PPC in a micronized form increases their lipophilicity to enhance their absorption and bioavailability.

Third, the same is the case for SAMe, as its systemic bioavailability is also low after oral administration. However, the patented micronized suspension in a delayed release capsule inside a capsule technology ensures the highest possible absorption of this critical ingredient.

Fourth, experimental and clinical studies have shown additive / synergistic effects of combinations of the active ingredients in Liverflo in comparison with the efficacy of the single active ingredients:
These are exemplary:
  • An association between Silymarin and SAMe (Samelive, Fidia/Italy), which has been brought to markets as a dietary supplement. 
  • A combination of PPC and glycyrrhicinic acid (Phosphogliv, Pharmstandard/Russia) has been successfully registered and marketed as a drug in Russia and surrounding nations. 
Clinical studies have demonstrated significant synergistic effects with SAMe and DLPC, SAMe and silymarin, silymarin and glycyrrhizin (Glycyrrhiza glabra), and silymarin and PPC, especially in alcoholic and non-alcoholic fatty liver and hepatic intoxication when combined.

This combination of four proven and synergistically active ingredients, formulated in a micronized PPC suspension, and delivered in a delayed release dual capsule technology can be considered a new breakthrough in hepatic functioning and protection.
When you take Liverflo…
  • You’re getting the most sophisticated and ONLY PATENTED All-Natural Liver Protection Breakthrough Available
  • You’re flooding your liver and every cell in your body with a Synergistic Combination of the best, most clinically valid, most purified, and most accepted ingredients available with the highest absorption and bioavailability possible.
  • You’re GOING TO GET RESULTS! 
So Let’s Sum it All Up
More than 500 clinical publications confirm the pharmacological results of the 4 compounds polyenylphosphatidylcholine, glycyrrhicinic acid, silymarin and s-adenosyl-L-methionine in Liverflo by:
  • inhibiting hepatic toxicity by air pollution, industrial toxins, nutrients and malnutrition, drugs, and hormone
  • reducing the risk to develop an alcoholic or non-alcoholic fatty liver disease, hepatitis and hepatic fibrosis or cirrhosis 
  • optimizing hepatocellular metabolic functions 
Why is the combination of the 4 active ingredients in Liverflo so special? Why does Liverflo have a synergistic unique mode of action beyond those described for each ingredient, leading to a breakthrough in hepatic functioning and protection?

First, the administration of PPC alone has been an approved drug since 1953 and is being sold today in over 50 countries around the world by a leading pharmaceutical company. (not available in the US)

Second, silymarin and Glycyrrhiza glabra have limited bioavailability, but co-administered with PPC in a micronized form increases their lipophilicity to enhance their absorption and bioavailability.

Third, the same is the case for SAMe, as its systemic bioavailability is also low after oral administration. However, the patented micronized suspension in a delayed release capsule inside a capsule technology ensures the highest possible absorption of this critical ingredient.

Fourth, experimental and clinical studies have shown additive / synergistic effects of combinations of the active ingredients in Liverflo in comparison with the efficacy of the single active ingredients:
These are exemplary:
  • An association between Silymarin and SAMe (Samelive, Fidia/Italy), which has been brought to markets as a dietary supplement. 
  • A combination of PPC and glycyrrhicinic acid (Phosphogliv, Pharmstandard/Russia) has been successfully registered and marketed as a drug in Russia and surrounding nations. 
Clinical studies have demonstrated significant synergistic effects with SAMe and DLPC, SAMe and silymarin, silymarin and glycyrrhizin (Glycyrrhiza glabra), and silymarin and PPC, especially in alcoholic and non-alcoholic fatty liver and hepatic intoxication when combined.

This combination of four proven and synergistically active ingredients, formulated in a micronized PPC suspension, and delivered in a delayed release dual capsule technology can be considered a new breakthrough in hepatic functioning and protection.
When you take Liverflo…
  • You’re getting the most sophisticated and ONLY PATENTED All-Natural Liver Protection Breakthrough Available
  • You’re flooding your liver and every cell in your body with a Synergistic Combination of the best, most clinically valid, most purified, and most accepted ingredients available with the highest absorption and bioavailability possible.
  • You’re GOING TO GET RESULTS! 
Recommended by Healthcare Practitioners
Well recognized Doctors, Healthcare Practitioners and Researchers are using and recommending LiverFlo to their patients for liver support and wholebody health! 
Robert W. MD - WI 
This is an awesome combination of ingredients and the most effective multi-ingredient liver formulation I have used.

Dr. Jerod J. PharmD - TX 
The product is great, I noticed a bile flush after taking it for a few days, Skin spots disappeared. I work out every day and noticed an increase in energy after taking liverflo.

Rhonda A. RD - NY 
The product has been extremely effective, it definitely has some good healing properties.

David K. MD - HI 
I noticed improvements immediately after administering to my patients.

Ann K. DO - MI 
I have seen tremendous results with my patients. I recommend this product to all of my at risk patients and also use it as an additional fat flush protocol during laser fat reduction therapy.

Rebecca C. MD - ME
LiverFlo is by far the best product I have used with my patients.  I see great changes in the numbers and in overall health after just several weeks of use. 

Recommended by Healthcare Practitioners
Well recognized Doctors, Healthcare Practitioners and Researchers are using and recommending LiverFlo to their patients for liver support and wholebody health! 
Robert W. MD - WI 
This is an awesome combination of ingredients and the most effective multi-ingredient liver formulation I have used.

Dr. Jerod J. PharmD - TX 
The product is great, I noticed a bile flush after taking it for a few days, Skin spots disappeared. I work out every day and noticed an increase in energy after taking liverflo.

Rhonda A. RD - NY 
The product has been extremely effective, it definitely has some good healing properties.

David K. MD - HI 
I noticed improvements immediately after administering to my patients.

Ann K. DO - MI 
I have seen tremendous results with my patients. I recommend this product to all of my at risk patients and also use it as an additional fat flush protocol during laser fat reduction therapy.

Rebecca C. MD - ME
LiverFlo is by far the best product I have used with my patients.  I see great changes in the numbers and in overall health after just several weeks of use. 

Purchase Using Your Health Savings (HSA) and Flexible Spending Account (FSA)

Great News! 
HSA & FSA Cards Now Accepted!
You can now purchase our professionally formulated products using your HSA or FSA Health Spending account. No Special Requirements are Necessary.  You can simply use your card the way you would your Visa, Mastercard or American Express.  

The best part about using your HSA or FSA Card is you get to utilize your pre-tax savings to purchase nutritional health products. This means you can save up to 37%. Savings are based on your tax bracket at filing. 
We do not require any paperwork or a doctor’s referral in order to process your purchase. You can just add your items to your shopping cart and check out using your HSA Card. It’s that Simple.

You may want to check with your HSA/FSA account provider to see if they require any documentation or record keeping for your supplement purchases. And you may want to have your doctor’s referral on file in case of an IRS audit. We have additional information below to assist you in making your HSA or FSA purchases. 

HSA/FSA Guide Reimbursement Form

The Nutrasal information guide and reimbursement form is provided for your convenience. It is not tax or legal advice. For more information about using your HSA Card for dietary supplements please visit www.irs.gov or your HSA Provider.

Purchase Using Your Health Savings (HSA) and Flexible Spending Account (FSA)

Great News! 
HSA & FSA Cards Now Accepted!
You can now purchase our professionally formulated products using your HSA or FSA Health Spending account. No Special Requirements are Necessary.  You can simply use your card the way you would your Visa, Mastercard or American Express.  

The best part about using your HSA or FSA Card is you get to utilize your pre-tax savings to purchase nutritional health products. This means you can save up to 37%. Savings are based on your tax bracket at filing. 
We do not require any paperwork or a doctor’s referral in order to process your purchase. You can just add your items to your shopping cart and check out using your HSA Card. It’s that Simple.

You may want to check with your HSA/FSA account provider to see if they require any documentation or record keeping for your supplement purchases. And you may want to have your doctor’s referral on file in case of an IRS audit. We have additional information below to assist you in making your HSA or FSA purchases. 

HSA/FSA Guide Reimbursement Form

The Nutrasal information guide and reimbursement form is provided for your convenience. It is not tax or legal advice. For more information about using your HSA Card for dietary supplements please visit www.irs.gov or your HSA Provider.

LiverFlo is Advanced Liver Science - US Patent (US 10,172,801 Bl)

LiverFlo was designed, formulated, and manufactured with our steadfast commitment to uncompromising quality and exceptional results. LiverFlo is produced in ISO certified and cGMP certified facilities. We adhere to stringent specifications and place a premium on purified, pharmaceutical grade ingredients.

We offer a 100% satisfaction guarantee. If for whatever reason you are not satisfied with the quality of our product(s), please return it for a full refund or a
replacement product.

References:


Gundermann K-J, A. Kuenker A, Kuntz E, Drozdzik M: Activity of essential phospholipids (EPL) from soybean in liver diseases. Pharmacol. Rep. 2011; 63: 643-659

 Kuntz E, Kuntz H-D: Hepatology - Textbook and Atlas. 3rd edition. Chapter 40. Springer press
 
Gundermann K-J, Kuntz E: Therapy of alcohol and drug-induced liver disease by plant-derived drugs. Progress in Hepato-Gastroenterol. 1999; IV: 49-58

Javed S, Kohli K, Ali M: Reassessing bioavailability of silymarin. Altern. Med. Rev. 2011; 16: 239-249

Udapurkar P, Bhusnure O, Kamble S, Biyani K: Phyto-phospholipid complex vesicles and herbal drugs: a promising drug delivery system. IJHM 2016; 4: 14-20

McMillan JM, Walle UK, Walle T: S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes. J. Pharm. Pharmacol. 2005; 57: 599-605

Testino G, Leone S, Ansaldi F, Borro P: Silymarin and S-adenosyl-L-methionine (SAMe): two promising pharmacological agents in case of chronic alcoholic hepatopathy. A review and a point of view. Minerva Gastroenterol. Dietol. 2013; 59: 341-356

Rasool M, Iqbal J, Malik A, Ramzan HS, et al: Hepatoprotective effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in combination: a possible synergy. Evid. Based Complement. Alternat. Med. 2014;2014:641597. doi: 10.1155/2014/641597
   
Archakov AI, Selzovskyi AP, Lisov VI, Tsyganov DI, et al: Phosphogliv: mechanisms of therapeutic action and clinical efficiency. Vopr. Med. Khimii 2002; 48: 139-151
  
Lieber CS, Leo MA, Cao Q, Mak KM, et al: The combination of S-adenosylmethionine and Dilinoleoylphosphatidylcholine attenuates non-alcoholic steatohepatitis produced in rats by a high fat diet. Nutr. Res. 2007; 27: 565-573
  
Cao Q, Mak KM, Lieber CS: DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting H202-mediated signal transduction. Liver International 2006; 26: 221-231
  
Cao Q, Mak KM, Lieber CS: DLPC and SAMe prevented a1(I)-collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione. Biochem. Biophys. Res. Commun. 2006; 350:50-55
  
Iakimchuk GN, Gendrikson LN: Study of clinical efficiency of essential phospholipids and silymarin combination in nonalcoholic and alcoholic steatohepatitis. Eksp. Klin. Gastroenterol. 2011; #7: 64-69
   
Gundermann K-J, Kuntz E: Therapy of alcohol and drug-induced liver disease by plant-derived drugs. Progress in Hepato-Pharmacol. 1999; 4: 49-58
  
Skakun NP, Stepanova NY: Efficacy of Legalon and Essentiale in "TCN" induced liver damage. Antibiot. Med. Biotekhnol. 1986; 31: 781-784
   
Leiber CS: S-Adenosyl-L-methionine: its role in the treatment of liver disorders - Am J Clin Nutr 2002;76(suppl):1183S-7S.
   
Anstee QM. et.al.: S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility Journal of Hepatology 2012 vol. 57 j 1097-1109
   
Alier R Et al. Eur Rev Med Pharmacol Sci 2015; 19(16):3118-24
   
Basarongulu M et al. Wold J astroenterol 2013;19(8):1166-72
   
Tappy L. Le KA. Clin Res Hepatol Gastroentoerol 2012;36(6):554-60
   
Blaising J et al. Cell Microbiol 2013;15(11):1866-82
   
Machado RM et. al. J Nutr 2010;140(6):2525-31

LiverFlo is Advanced Liver Science - US Patent (US 10,172,801 Bl)

LiverFlo was designed, formulated, and manufactured with our steadfast commitment to uncompromising quality and exceptional results. LiverFlo is produced in ISO certified and cGMP certified facilities. We adhere to stringent specifications and place a premium on purified, pharmaceutical grade ingredients.

We offer a 100% satisfaction guarantee. If for whatever reason you are not satisfied with the quality of our product(s), please return it for a full refund or a
replacement product.

References:


Gundermann K-J, A. Kuenker A, Kuntz E, Drozdzik M: Activity of essential phospholipids (EPL) from soybean in liver diseases. Pharmacol. Rep. 2011; 63: 643-659

 Kuntz E, Kuntz H-D: Hepatology - Textbook and Atlas. 3rd edition. Chapter 40. Springer press
 
Gundermann K-J, Kuntz E: Therapy of alcohol and drug-induced liver disease by plant-derived drugs. Progress in Hepato-Gastroenterol. 1999; IV: 49-58

Javed S, Kohli K, Ali M: Reassessing bioavailability of silymarin. Altern. Med. Rev. 2011; 16: 239-249

Udapurkar P, Bhusnure O, Kamble S, Biyani K: Phyto-phospholipid complex vesicles and herbal drugs: a promising drug delivery system. IJHM 2016; 4: 14-20

McMillan JM, Walle UK, Walle T: S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes. J. Pharm. Pharmacol. 2005; 57: 599-605

Testino G, Leone S, Ansaldi F, Borro P: Silymarin and S-adenosyl-L-methionine (SAMe): two promising pharmacological agents in case of chronic alcoholic hepatopathy. A review and a point of view. Minerva Gastroenterol. Dietol. 2013; 59: 341-356

Rasool M, Iqbal J, Malik A, Ramzan HS, et al: Hepatoprotective effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in combination: a possible synergy. Evid. Based Complement. Alternat. Med. 2014;2014:641597. doi: 10.1155/2014/641597
   
Archakov AI, Selzovskyi AP, Lisov VI, Tsyganov DI, et al: Phosphogliv: mechanisms of therapeutic action and clinical efficiency. Vopr. Med. Khimii 2002; 48: 139-151
  
Lieber CS, Leo MA, Cao Q, Mak KM, et al: The combination of S-adenosylmethionine and Dilinoleoylphosphatidylcholine attenuates non-alcoholic steatohepatitis produced in rats by a high fat diet. Nutr. Res. 2007; 27: 565-573
  
Cao Q, Mak KM, Lieber CS: DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting H202-mediated signal transduction. Liver International 2006; 26: 221-231
  
Cao Q, Mak KM, Lieber CS: DLPC and SAMe prevented a1(I)-collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione. Biochem. Biophys. Res. Commun. 2006; 350:50-55
  
Iakimchuk GN, Gendrikson LN: Study of clinical efficiency of essential phospholipids and silymarin combination in nonalcoholic and alcoholic steatohepatitis. Eksp. Klin. Gastroenterol. 2011; #7: 64-69
   
Gundermann K-J, Kuntz E: Therapy of alcohol and drug-induced liver disease by plant-derived drugs. Progress in Hepato-Pharmacol. 1999; 4: 49-58
  
Skakun NP, Stepanova NY: Efficacy of Legalon and Essentiale in "TCN" induced liver damage. Antibiot. Med. Biotekhnol. 1986; 31: 781-784
   
Leiber CS: S-Adenosyl-L-methionine: its role in the treatment of liver disorders - Am J Clin Nutr 2002;76(suppl):1183S-7S.
   
Anstee QM. et.al.: S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility Journal of Hepatology 2012 vol. 57 j 1097-1109
   
Alier R Et al. Eur Rev Med Pharmacol Sci 2015; 19(16):3118-24
   
Basarongulu M et al. Wold J astroenterol 2013;19(8):1166-72
   
Tappy L. Le KA. Clin Res Hepatol Gastroentoerol 2012;36(6):554-60
   
Blaising J et al. Cell Microbiol 2013;15(11):1866-82
   
Machado RM et. al. J Nutr 2010;140(6):2525-31

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